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New Drug for Advanced Breast Cancer puts Tumor Growth on ‘Pause’

 
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new advanced breast cancer drug pauses tumor growth Auremar/PhotoSpin

Dr. Dennis Slamon, professor of Medicine at JCCC and director of the Revlon/UCLA Women’s Cancer Research Program is the study’s senior author. He says the drug represents a new and “exciting” approach to breast cancer treatment.

In the stage II clinical trials, among 165 breast cancer patients with measureable ER+ disease, 45 percent received the combination had confirmed responses, compared to 31 percent with letrozole alone.

The study showed clinical benefit rates — tumor shrinkage and/or stable disease for a minimum of six months — were 70 percent and 44 percent, respectively.

Lynette Summerill is an award-winning writer and Scuba enthusiast who lives in San Diego with her husband and two beach loving dogs. In addition to writing about cancer-related issues for EmpowHER, her work has been seen in numerous publications.

Sources:

The Group Room. Richard S. Finn, MD explains Combination Of PD 0332991 and Letrozole Phase II Results at 35th annual CTRC-AACR San Antonio Breast Cancer Symposium. (video)
http://thegrouproom.tv/richard-s-finn-md-the-combination-of-pd-0332991-and-letrozole-phase-ii-results/2013/03/03

Combination therapy with experimental drug improves outlook for breast cancer patients. UCLA Jonnson Comprehensive Cancer Center. 2 Dec. 2012. Shaun Mason.
http://newsroom.ucla.edu/portal/ucla/ucla-translational-researchers-241247.aspx and http://newsroom.ucla.edu/portal/ucla/breast-cancer-drug-receives-breakthrough-245162.aspx

Reviewed April 23, 2013
by Michele Blacksberg RN
Edited by Jody Smith

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Breast cancer became the most common issue in woman specially in a teenager females. The drug palbociclib from pfizer is really interesting and it shown it's effect on it's testing period. The FDA has given a clean chit to this drug and now available for testing. The combination of palbociclib with letrozole shows a drastic effect in woman breast cancer. I hope this research will go more further and will find more effective solution to prevent and to cure from breast cancer.
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April 29, 2013 - 10:51am
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