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Grapefruit-Drug Interactions Dangerous for Some, Useful for Others

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interactions between drugs and grapefruit may be dangerous for some Evgeny Karandaev/PhotoSpin

For more online information on food-drug interactions, visit the U.S. National Library of Medicine or National Institutes of Health Clinical Center Drug-Nutrient Interaction Task Force.

Lynette Summerill is an award-winning writer and Scuba enthusiast who lives in San Diego with her husband and two beach loving dogs. Besides writing about cancer-related issues for EmpowHER, her work has been seen in newspapers and magazines around the world.


Grapefruit-medication interactions: Forbidden fruit or avoidable consequences? David G. Bailey, George Dresser, and J. Malcolm O. Arnold. Canadian Medical Association Journal. First published online November 26, 2012, doi: 10.1503/cmaj.120951. Access online (requires subscription or pay-for-view)

Phase I Studies of Sirolimus Alone or in Combination with Pharmacokinetic Modulators in Advance Cancer Patients. Ezra E.W. Cohen et al. Clinical Cancer Research. Published OnlineFirst August 7, 2012; doi: 10.1158/1078-0432.CCR-12-0110. Abstract at:

“Grapefruit can interact with many drugs to cause severe effects or death: study. Sheryl Ubelacker, Ottawa Citizen. 28 Nov. 2012. Accessed online at:

Reviewed December 11, 2012
by Michele Blacksberg RN
Edited by Jody Smith

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.