Does anyone know the difference between Roseola and Hands, Foot, and Mouth disease. A girl at daycare had Roseola, but my daughter was diagnosed with HFMD. I noticed it on her bottom first. We haven't gone out until Wednesday night and that's when I noticed it. I don't think she could have caught it within the hour we were at the store, but apparently noone noticed it at daycare when I picked it up.