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Causes
The exact cause is unknown.
The following conditions are commonly associated with fibromyalgia:
- Depression and anxiety
- Muscle pain
- Chronic headache, such as tension headaches (frequently beginning with neck discomfort)
- Numbness and tingling
- Sensation of swollen hands and edema (swelling usually in the feet, ankles, and legs)
- Nocturnal myoclonus (moving legs involuntarily during sleep)
- Irritable bowel syndrome
- Complex regional pain syndrome
- Substance abuse
- Premenstrual syndrome
- Female urethral syndrome (irritable bladder)
- Raynaud's disease
Risk Factors
A risk factor is something that increases your chance of getting fibromyalgia. Risk factors include:
- Sex: female
- Age: 20-60 years old
- Physical or mental stress
- Physical trauma (eg, accident, injury, or severe illness)
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2026 EBSCO Publishing All rights reserved.