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Androgen Supplementation in Older Women: Too Much Hype, Not Enough Data: Part 4

 
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GnRH agonist or antagonist analogs, often used for treating endometriosis and other reproductive disorders, suppress gonadotropin secretion. Glucocorticoid therapy suppresses corticotropin releasing hormone (CRH) and adrenocorticotropic hormone (ACTH) and leads to low levels of cortisol, DHEA, DHEAS and androstenedione. In addition, pharmacologic doses of glucocorticoids in amounts greater than 10 mg prednisone daily or equivalent doses of other glucocorticoids directly inhibit ovarian
steroidogenesis. Human immunodeficiency virus infection and chronic illness are examples of systemic causes of androgen deficiency.

Link to article: http://www.goodhormonehealth.com/symptoms/androgen.pdf

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