Who doesn't have a story about working hard to lose weight? Skipping desserts, exercising like a dog, whatever -- only to have that weight sneak back up on you six months later?
Well, the good news is that a chemical called leptin, "a hormone secreted by fat cells may be behind the gain."
http://www.azstarnet.com/sn/health/248188.php
"When humans (and rodents) lose 10 percent or more of their body weight, leptin falls rapidly and sets off a cascade of physiological changes that act to put weight back on. Skeletal muscles work more efficiently, thyroid and other hormones are reduced — all so the body burns 15 percent to 20 percent fewer calories, enough to put back 25 pounds or more a year."
Have you ever lost and gained weight? What did you do about it? Did you give it another try?