I am 43 years old and have been been diagnosed with depression and taking zoloft for 14 years (that is until about 3 months ago) My doctor told me to face facts that I was on zoloft for the rest of my life until he finally sent me to a psychiatrist as I was having side effects of racing thoughts. In October I had my first visit with the psych and he told me I should never have been on zoloft for such a long time and he took me off it immediately...only for me to have a horrible reaction to the new drug he tried-olanzapine. I gained 20+ pounds which made my depression even worse. I was constantly crying for no real reason and got to the point that I didn't know why I was even living. I finally got ahold of the psych and he basically got mad at me and told me to get off the pills and "tough it out" well I told him i couldn't as my life was such a mess--I haven't gotten up before 9 in the past 15 years and have never got up to feed my kids before school. I feel like such a loser. I have a very short day and by 2pm I am in my pyjamas laying in bed. I rarely do housekeeping and I don't have a real job. Anyhow, I have since been put on Pristiq which has helped with the "losing weight", but has me looking at life again like....why bother. I have been taking pristiq for about 2 weeks now, and don't have another dr. apt. until the 12th of february. I find myself alone with no friends. I was hopeing to get some advice from this site. Please let me knwo what you think.