My mother had a complete hysterectomy in the late 90's and had adverse reactions to Premarin. Her doctor tried lowering the dosages and methods (from pill to patch) and she still didn't like it. She stopped taking the HRT completely and hasn't taken anything since, including OTC medications. She is 53 now and still has hot flashes. The major problem she has though is the tendency to have giant mood swings every three months or so. She will be happy and giggly for a while and then something will make her mad, and she will blow up and blow everything out of proportion.
She has always had a tendency to do this, but I can't remember if it started after her surgery or before, as I'm only 24. Has anyone else had this problem? Should she try taking another HPT or something OTC? She has gone so long without estrogen, could it be affecting her mentally as well as physically?