Researchers from the University of Minnesota, University of Toronto, Yale University and The Mind Research Network in Albuquerque, New Mexico worked together to study personality traits and areas of the brain.
"The researchers found evidence in the brain for four of the 'Big Five personality traits': extroversion, neuroticism, agreeableness, and conscientiousness. They looked at the volumes of various brain regions to see how greater or smaller volumes might be connected to personality traits."
The medial orbitofrontal cortex which processes reward information, may be linked with extroversion. Brain regions that are connected with threat and punishment may be linked with neuroticism.
Brain regions that process information about other people's state of mind may be linked with agreeableness. The lateral prefrontal cortex, which handles planning and self-control may be linked with conscientiousness.
The researchers looked for but did not find a connection between areas of the brain and openness or intellect. Openness/intellect is the trait associated with creativity and imagination, and with people who are philosophical and intellectually active.
http://pagingdrgupta.blogs.cnn.com/2010/06/22/personality-shows-up-in-brain-structure/?utm_source