OMG.. I got realy sick from the pellet, wen to ER they coulnt do anything. So I had to wait 2 weeks for the nasua, gastritis horrible symptoms to go away.. So 3 months later my doctor gave me the creams, been on them 1 week again throwingup and I am on a low dose, moody, its horrible... these are not natural this is the same as HRT .. Don't buy in that these are natural at all