Pronounced: Dif-THEER-e-uh
Diphtheria is a highly contagious and life-threatening infection caused by bacteria. The infection most commonly attacks the mucus membranes associated with the breathing system (the tonsils, throat, and nose) and can also infect the skin. In addition, some types of the bacteria can cause damage to the heart, nerves, kidneys, and brain.
The vaccine for diphtheria is safe and is very effective at preventing the disease. A series of shots are given during childhood, then booster shots are required every ten years to keep the immunity strong.
Before vaccines and medications were available to prevent and treat the disease, nearly one out of ten people died. Diphtheria was the leading cause of death among children.
Diphtheria is a medical emergency that requires immediate care from your doctor. Not everyone who gets diphtheria shows signs of illness, though they may be able to infect others. The sooner it is treated, the more favorable the outcome.
Diphtheria is caused by the bacteria Corynebacterium diphtheriae . The infection spreads from person to person through contact with:
A risk factor is something that increases your chance of getting a disease or condition. Risk factors include:
Signs and symptoms of diphtheria usually begin 2 to 5 days after a person is infected. The most telltale sign of diphtheria is a gray covering on the back of the throat, which can detach and block the airway. If left untreated, the bacteria can produce a poison that spreads through the body causing damage to the heart, nerves, and kidneys.
Symptoms include:
Your doctor will ask about your symptoms and medical history, and perform a physical exam. Diphtheria will be suspected if the throat and tonsils are covered with a gray membrane. Tests to confirm a diagnosis may include:
Talk with your doctor about the best treatment plan for you. If your doctor suspects diphtheria, your treatment will start immediately, even before the lab results are returned. Treatment options include the following:
To help reduce your chances of getting diphtheria, take the following steps:
RESOURCES:
Centers for Disease Control and Prevention
National Immunization Program
http://www.cdc.gov/nip
National Coalition for Adult Immunization
http://www.nfid.org
National Foundation of Infectious Diseases (NFID)
http://www.nfid.org
National Institute of Allergy and Infectious Diseases
http://www3.niaid.nih.gov
World Health Organization
http://www.who.int
CANADIAN RESOURCES:
BC Health Guide
http://www.bchealthguide.org
Caring for Kids, The Canadian Paediatric Society
http://www.caringforkids.cps.ca
References:
Beers MH, Fletcher AJ, Jones TV, et al. The Merck Manual of Medical Information: Second Home Edition . Whitehouse Station, NJ: Merck Research Laboratories; 2003.
Epidemiology and Prevention of Vaccine-Preventable Diseases . 8th ed (2005). Published by the National Immunization Program, Centers for Disease Control and Prevention, US Department of Health and Human Services. Available at: http://www.cdc.gov/nip/publications/pink/dip.pdf.
Last reviewed November 2008 by David L. Horn, MD, FACP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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