Pronounced: diabetes -in-' sip-d-s
There are two forms of diabetes insipidus (DI):
ADH controls the amount of water reabsorbed by the kidneys. ADH is made in the hypothalamus of the brain. The pituitary gland , at the base of the brain, stores and releases ADH.
The following factors increase your chance of developing diabetes insipidus:
If you have any of these, do not assume it is due to diabetes insipidus. These symptoms may be caused by other health conditions. See your doctor, if you experience any one of them:
Your doctor will ask about your symptoms and medical history. A physical exam may be done.
Tests may include the following:
Talk with your doctor about the best plan for you. Treatment options include the following:
In both CDI and NDI, symptoms can often be reduced by:
RESOURCES:
Diabetes Insipidus Foundation
http://www.diabetesinsipidus.org
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
http://kidney.niddk.nih.gov
Nephrogenic Diabetes Insipidus Foundation
http://www.ndif.org
CANADIAN RESOURCES:
Canadian Diabetes Association
http://www.diabetes.ca
Health Canada
http://www.hc-sc.gc.ca/index_e.html
References:
Diabetes insipidus. DynaMed website. Available at:
http://www.dynamicmedical.com/dynamed.nsf?opendatabase
. Accessed September 20, 2005.
Diabetes insipidus. MedlinePlus Medical Encyclopedia website. Available at:
http://www.nlm.nih.gov/medlineplus/ency/article/000377.htm
. Accessed September 18, 2005.
Garofeanu CG, Weir M, Rosas-Arellano MP, et al. Causes of reversible nephrogenic diabetes insipidus: a systematic review. Am J Kidney Dis . 2005;45:626-37.
Rivkees SA, Dunbar N, Willson TA: The management of central diabetes insipidus in infancy: desmopressin, low renal solue load formula, thazide diuretics. J Pediatr Endocrinol Metab . 2007;20:459-69.
The Merck Manual of Diagnosis and Therapy . 15th ed. Rahway, NJ: Merck Sharp and Dohme Research Laboratories; 1987.
Majzoub JA, Srivatsa A: Diabetes insipidus: clinical and basic aspects. Pediatr Endocrinol Rev 2006;Suppl 1: 60-5.
Sands JM, Bichet DG. Nephogenic diabetes insipidus. Annals Int Med . 2006;144:186-194.
Toumba M, Stanhope R. Morbidity and mortality associated with vasopressin analogue treatment. Pediatr Endocrinol Metab . 2006;19:197-201.
Last reviewed January 2009 by Rosalyn Carson-DeW¹itt, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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