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The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included, so ask your doctor if you need to take any special precautions. Use each of these medications as recommended by your doctor, or according to the instructions provided. If you have further questions about usage or side effects, contact your doctor.
Anxiolytics (anti-anxiety medications) and antidepressants can help ease the symptoms of panic disorder. They are often used in combination with counseling. Depending on the person, medication may be advised only for a short time or for a long period of time. Medication helps relieve symptoms but should not take the place of counseling (psychotherapy), which can address the root of the problem.
Monoamine Oxidase Inhibitors (MAOIs)
Selective Serotonin Reuptake Inhibitors (SSRIs)
The FDA advises that people taking antidepressants should be closely observed. For some, the medications have been linked to worsening symptoms and suicidal thoughts. These adverse effects are most common in young adults. The effects tend to occur at the beginning of treatment or when there is an increase or decrease in the dose.
Although the warning is for all antidepressants, of most concern are the SSRI class such as:
For more information, please visit: http://www.fda.gov/cder/drug/antidepressants/
Common names include:
Benzodiazepines relieve symptoms of panic disorder by enhancing the function of gamma aminobutyric acid (GABA), a neurotransmitter thought to be abnormal in people with anxiety disorders. These drugs produce a sedative effect, relieve physical symptoms, such as muscle tension, and often cause drowsiness and lethargy. The advantage of benzodiazepines is that they are fast-acting and useful for treating acute anxiety , panic, and insomnia . When stopping the medication, you should slowly taper off over a period of weeks or months under a doctor’s supervision.
These drugs can be habit-forming when used long-term or in excess, in which case they may cause withdrawal symptoms such as “rebound panic,” anxiety, irritability, and insomnia when discontinued. If you have previously had a problem with substance abuse ( alcoholism , drug addiction ), discuss with your doctor whether or not you should use benzodiazepines.
Do not take benzodiazepines with alcohol or other sedating drugs. Do not take if you must drive a vehicle or operate equipment. These drugs should not be taken in combination with certain oral antifungal medications or by people with certain types of glaucoma .
Possible side effects include:
Common names include:
Monoamine oxidase inhibitors (MAOIs) are a type of antidepressant that relieve symptoms of panic disorder by preventing the breakdown of serotonin and noradrenaline. They are especially effective for people whose symptoms have not responded to other treatments. Improvement is usually seen in 2-6 weeks after beginning treatment. MAOIs are not addictive.
MAOIs can cause adverse reactions when combined with many other types of drugs, such as:
Ask your doctor and pharmacist for a complete list of what to avoid.
At minimum, a 2-5 week break is necessary between stopping MAOIs and starting another antidepressant. MAOIs can cause birth defects and should not be taken by pregnant women.
When taking MAOIs, you should not eat food with a high tyramine content, such as:
Possible side effects include:
Common names include:
Tricyclic antidepressants regulate the neurotransmitters serotonin and/or noradrenalin in the brain. Tricyclic antidepressants are not addictive.
Possible side effects include:
*** See note above.
Common names include:
Selective serotonin reuptake inhibitors (SSRIs) affect the concentration of the neurotransmitter serotonin, which plays a role in anxiety. Although they are considered antidepressants, SSRIs have been used effectively for the treatment of panic and other anxiety disorders. Improvement is usually seen in 4-6 weeks after beginning treatment. SSRIs are not addictive. Do not take an SSRI if you have taken an MAOI in the last 2-5 weeks.
Possible side effects include:
Common brand names include:
Atypical antidepressants affect the concentration of the neurotransmitter serotonin and can be effective in treating panic. Improvement is usually seen in 4-6 weeks after beginning treatment.
Possible side effects include:
Consultation with a specially trained mental health professional is recommended if you do not respond to treatment with medications. A mental health professional can help clarify the diagnosis and determine if another psychiatric disorder is present. He can also make recommendations about psychotherapy and changes in medications.
If you are taking medications, follow these general guidelines:
Contact your doctor if you have any side effects that are troublesome and persistent or if you have any questions about your medications.
References
Anxiety Disorders Association of America website. Available at: http://www.adaa.org/ .
Abnormal Psychology and Modern Life . 11th ed. Allyn and Bacon; 2000.
USP DI. 21st ed. Micromedex; 2001.
Last reviewed March 2009 by Rosalyn Carson-DeWitt, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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