Brucellosis is a rare bacterial disease that causes intermittent fevers. Brucellosis is primarily passed among animals, but people can acquire this disease from domesticated animals. It results in flu-like symptoms, and may cause long-lasting symptoms. There are only about 100 to 200 cases of brucellosis in humans in the US each year.
Brucellosis is caused by the bacterium Brucella. This bacterium infects domesticated animals. It can be spread to humans through:
A risk factor is something that increases your chance of getting a disease or condition. Risk factors for brucellosis include:
Symptoms of brucellosis usually appear within two weeks of infection. Symptoms can appear from five days to several months after infection.
In early stage, symptoms may include:
As it progresses, brucellosis causes a severe fever (104° F to 105° F). This fever occurs in the evening along with severe sweating. It becomes normal or near normal in the morning, and usually begins again at night.
This intermittent fever usually lasts 1 to 5 weeks, after which symptoms usually subside or disappear for two days to two weeks. Then the fever recurs. In some patients, this fever recurs only once. In others, the disease becomes chronic, and the fever recurs, subsides, and then recurs again repeatedly over months or years.
In later stages, brucellosis can cause:
Patients usually recover within 2 to 5 weeks. Rarely, complications can develop. These may include:
Brucellosis is also believed to cause a high rate of miscarriage during early pregnancy in infected women.
Your doctor will ask about your symptoms and medical history, and perform a physical exam. Tests may include the following:
Many patients recover from brucellosis on their own. However, early diagnosis and treatment can reduce the risk of complications and infection. Talk with your doctor about the best treatment plan for you. Treatment options include:
Your doctor may prescribe one or more antibiotics (usually doxycycline and rifampin) to control and prevent relapses of brucellosis. Antibiotics are given for up to six weeks.
To help reduce your chances of getting brucellosis, take the following steps:
RESOURCES:
Centers for Disease Control and Prevention
http://www.cdc.gov
National Foundation for Infectious Diseases
http://www.nfid.org
United States Department of Agriculture
http://www.usda.gov
CANADIAN RESOURCES:
Communicable Disease Control Unit
http://www.gov.mb.ca/health/publichealth/cdc/index.html
Public Health Agency of Canada
http://www.phac-aspc.gc.ca
References:
Brucellosis. Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/ncidod/dbmd/diseaseinfo/brucellosis_g.htm#top . Accessed February 14, 2007.
Brucellosis. Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/ncidod/dbmd/diseaseinfo/brucellosis_g.html . Accessed November 11, 2005.
Facts about brucellosis. US Department of Agriculture website. Available at: http://www.aphis.usda.gov/vs/nahps/brucellosis/ . Accessed Accessed February 14, 2007.
Facts about brucellosis. US Department of Agriculture website. Available at: http://www.aphis.usda.gov/vs/nahps/brucellosis/ . Accessed November 11, 2005.
The Merck Manual of Medical Information . Simon and Schuster, Inc.; 2000.
Last reviewed November 2008 by David L. Horn, MD, FACP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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