Chemotherapy may, but does not always, affect sexual organs (testis in men, vagina and ovaries in women) and functioning in both men and women. The side effects that might occur depend on the drugs used and the person's age and general health.
Chemotherapy drugs may lower the number of sperm cells and reduce their ability to move. These changes can result in infertility, which may be temporary or permanent. Infertility affects a man's ability to father a child, but not a man's ability to have sexual intercourse. Other possible effects of these drugs are problems with getting or keeping an erection and damage to the chromosomes, which could lead to birth defects.
Anticancer drugs can affect the ovaries and reduce the amount of hormones they produce. Some women find that their menstrual periods become irregular or stop completely while having chemotherapy. Related side effects may be temporary or permanent.
These tips may help:
These tips may help:
Although pregnancy may be possible during chemotherapy, it still is not advisable because some anticancer drugs may cause birth defects. Doctors advise women of childbearing age, from the teens through the end of menopause, to use some method of birth control throughout their treatment, such as condoms, spermicidal agents, diaphragms, or birth control pills. Birth control pills may not be appropriate for some women, such as those with breast cancer . Ask your doctor about these contraceptive options.
If a woman is pregnant when her cancer is discovered, it may be possible to delay chemotherapy until after the baby is born. For a woman who needs treatment sooner, the possible effects of chemotherapy on the fetus need to be evaluated.
Sexual feelings and attitudes vary among people during chemotherapy. Some people find that they feel closer than ever to their partners and have an increased desire for sexual activity. Others experience little or no change in their sexual desire and energy level. Still others find that their sexual interest declines because of the physical and emotional stresses of having cancer and getting chemotherapy. These stresses may include:
A partner's concerns or fears also can affect the sexual relationship. Some may worry that physical intimacy will harm the person who has cancer. Others may fear that they might "catch" the cancer or be affected by the drugs. Both you and your partner should feel free to discuss sexual concerns with your doctor, nurse, social worker, or other counselor who can give you the information and the reassurance you need.
You and your partner also should try to share your feelings with each other. If talking to each other about sex, cancer, or both, is hard, you may want to speak to a counselor who can help you talk more openly. People who can help include psychiatrists, psychologists, social workers, marriage counselors, sex therapists, and members of the clergy.
If you were comfortable with and enjoyed sexual relations before starting chemotherapy, chances are you will still find pleasure in physical intimacy during your treatment. You may discover, however, that intimacy changes during treatment. Hugging, touching, holding, and cuddling may become more important, while sexual intercourse may become less important. Remember that what was true before you started chemotherapy remains true now: there is no one "right" way to express your sexuality. You and your partner should decide together what gives both of you pleasure.
RESOURCES:
American Cancer Society
http://www.cancer.org
National Cancer Institute
http://www.cancer.gov
CANADIAN RESOURCES:
BC Cancer Agency
http://www.bccancer.bc.ca/default.htm
Canadian Cancer Society
http://www.cancer.ca
References:
National Cancer Institute website. Available at: http://www.cancer.gov .
Dolmans, MM, Demylle, D, Martinez-Madrid, B, Donnez, J. Efficacy of in vitro fertilization after chemotherapy. Fertil Steril . 2005; 83:897.
Ginsburg, ES, Yanushpolsky, EH, Jackson, KV. In vitro fertilization for cancer patients and survivors. Fertil Steril . 2001; 75:705.
Veeck, LL, Bodine, R, Clarke, RN, et al. High pregnancy rates can be achieved after freezing and thawing human blastocysts. Fertil Steril. 2004; 82:1418
Walshe, JM, Denduluri, N, Swain, SM. Amenorrhea in premenopausal women after adjuvant chemotherapy for breast cancer. J Clin Oncol . 2006; 24:5769.
Last reviewed March 2008 by Marcin Chwistek, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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