Brand Name(s):

  • Pro-Banthine®

WHY is this medicine prescribed?

Propantheline is used with other medication to treat ulcers. Propantheline is in a class of medications called anticholinergics. It works by slowing the movement of food through the stomach and intestines and decreasing the amount of acid made by the stomach.

HOW should this medicine be used?

Propantheline comes as a tablet to take by mouth. Propantheline is usually taken four times a day, 30 minutes before meals and at bedtime. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take propantheline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What SPECIAL PRECAUTIONS should I follow?

Before taking propantheline,

  • tell your doctor and pharmacist if you are allergic to propantheline, any other medications, or any of the ingredients in propantheline tablets. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements,and herbal products you are taking or plan to take. Be sure to mention any of the following: amantadine (Symmetrel), antihistamines, digoxin (Lanoxin), disopyramide (Norpace), glutethimide (Doriden), levodopa (Larodopa, Sinemet), meperidine (Demerol), extended-release potassium chloride tablets, quinidine (Quinaglute), tranquilizers, and medications for depression and Parkinson's disease. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had colitis; glaucoma; an enlarged prostate gland; high blood pressure; an overactive thyroid gland; liver, heart, blood vessel, or kidney disease; myasthenia gravis; difficulty urinating; or asthma, bronchitis, emphysema, or lung disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking propantheline, call your doctor.
  • talk to your doctor about the risks and benefits of taking propantheline if you are 65 years of age or older. Older adults should not usually take propantheline because it is not as safe or effective as other medications that can be used to treat the same condition.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking propantheline.
  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
  • ask your doctor about the safe use of alcohol while you are taking this medication. Alcohol can make the side effects of propantheline worse.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do IF I FORGET to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Propantheline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dry mouth
  • increased sensitivity of your eyes to light
  • dizziness
  • nervousness
  • difficulty sleeping
  • headache
  • loss of sense of taste
  • upset stomach
  • vomiting
  • bloating
  • confusion (especially in the elderly)
  • blurred vision
  • constipation

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

  • fast heartbeat
  • heart palpitations
  • eye pain
  • difficulty urinating
  • skin rash
  • itching

Propantheline may cause other side effects. Call your doctor if you have any unusual problems while you are taking propantheline.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at Web Site] or by phone [1-800-332-1088].

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What should I do in case of OVERDOSE?

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What OTHER INFORMATION should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: January 1, 2011.