I am 51 years old and have been taking prempro (lowest dose) on and off for two years. Recently, I quit taking it completely about 4 weeks ago. Now I am having severe hot flashes day and night, panic attacks, extremely stressed out, suffering from lack of sleep, emotionally a wreck and plain and simply depressed and unhappy. I have tried a cream, Femorone, and it seemedto make me very irritable. Help! Michelle