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(reply to Anonymous)

Yes, it does take days to weeks for Boniva to be eliminated from the body, as it occurs in phases (37-157 hours, to be exact).

According to the manufacturers on the pharmacodynamics of Boniva, the half-life elimination occurs in phases, and the terminal half life depends on the dosage, re-uptake of the drug by the bones, and other factors. "The observed apparent terminal half-life for the 150 mg ibandronate tablet upon oral administration to healthy postmenopausal women ranges from 37 to 157 hours."

(Just so everyone knows the definitions: The duration of action of a drug is known as its half life. This is the period of time required for the concentration or amount of drug in the body to be reduced by one-half. The terminal half-life is the amount of drug concentration in blood plasma, divided by two. I know...confusing terminology!)

August 30, 2009 - 2:32pm

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