There are some clinical research studies that have looked at comparing bioidentical HRT to HRT. I am trying to find some "full-text" versions for you to review, but in the meantime, here is a start from peer-reviewed medical journals, or perhaps you can gain access to these journals through your local library or nearby university health science library.
I search for all peer-reviewed and evidence-based journals on PubMed, then use that information as a starting place: have these results been replicated? What does my doctor or other trusted health care provider say about this information?
1. Curcio, Jessica J et al (2006). Is Bio-Identical Hormone Replacement Therapy Safer than Traditional Hormone Replacement Therapy?: A Critical Appraisal of Cardiovascular Risks in Menopausal Women. Treatments in Endocrinology. 5(6):367-374.
2. Moskowitz, D. (2006). A comprehensive review of the safety and efficacy of bioidentical hormones for the management of menopause and related health risks. Alternative medicine review: a journal of clinical therapeutic September 11(3):208-23.
To view abstract online: http://www.ncbi.nlm.nih.gov/sites/entrez
Direct quote from this article: "This article reviews the disparities between synthetic and bioidentical estrogens and progestins/progesterone with respect to safety and efficacy; special attention is devoted to clinical outcomes in the breast, endometrium, bone, cardiovascular system, and brain. The studies reviewed suggest bioidentical progesterone does not have a negative effect on blood lipids or vasculature as do many synthetic progestins, and may carry less risk with respect to breast cancer incidence. Studies of both bioidentical estrogens and progesterone suggest a reduced risk of blood clots compared to non-bioidentical preparations. Bioidentical hormone preparations have demonstrated effectiveness in addressing menopausal symptoms. The author advocates for continued research on bioidentical hormones and concludes there is currently sufficient evidence to support their preferred use over that of their synthetic cousins."
Journals you may like to search (review who sponsors the journal, as not all may be peer-reviewed or evidence-based):
- Alternative medicine review: a journal of clinical therapeutic
- Alternative therapies in health and medicine
- Evidence-based complementary and alternative medicine: eCAM
- Integrative medicine: integrating conventional and alternative medicine
- Journal of alternative and complementary medicine
- Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Lastly---let me know if this is too overwhelming for you, and I can do some more research for you (instead of listing journals)! I did not know how overloaded you wanted to be with information, and I can summarize what I find!
This is such a great question...I'm sure others will chime in as well!!
Comment Reply
There are some clinical research studies that have looked at comparing bioidentical HRT to HRT. I am trying to find some "full-text" versions for you to review, but in the meantime, here is a start from peer-reviewed medical journals, or perhaps you can gain access to these journals through your local library or nearby university health science library.
I search for all peer-reviewed and evidence-based journals on PubMed, then use that information as a starting place: have these results been replicated? What does my doctor or other trusted health care provider say about this information?
1. Curcio, Jessica J et al (2006). Is Bio-Identical Hormone Replacement Therapy Safer than Traditional Hormone Replacement Therapy?: A Critical Appraisal of Cardiovascular Risks in Menopausal Women. Treatments in Endocrinology. 5(6):367-374.
2. Moskowitz, D. (2006). A comprehensive review of the safety and efficacy of bioidentical hormones for the management of menopause and related health risks. Alternative medicine review: a journal of clinical therapeutic September 11(3):208-23.
To view abstract online: http://www.ncbi.nlm.nih.gov/sites/entrez
Direct quote from this article: "This article reviews the disparities between synthetic and bioidentical estrogens and progestins/progesterone with respect to safety and efficacy; special attention is devoted to clinical outcomes in the breast, endometrium, bone, cardiovascular system, and brain. The studies reviewed suggest bioidentical progesterone does not have a negative effect on blood lipids or vasculature as do many synthetic progestins, and may carry less risk with respect to breast cancer incidence. Studies of both bioidentical estrogens and progesterone suggest a reduced risk of blood clots compared to non-bioidentical preparations. Bioidentical hormone preparations have demonstrated effectiveness in addressing menopausal symptoms. The author advocates for continued research on bioidentical hormones and concludes there is currently sufficient evidence to support their preferred use over that of their synthetic cousins."
Journals you may like to search (review who sponsors the journal, as not all may be peer-reviewed or evidence-based):
- Alternative medicine review: a journal of clinical therapeutic
- Alternative therapies in health and medicine
- Evidence-based complementary and alternative medicine: eCAM
- Integrative medicine: integrating conventional and alternative medicine
- Journal of alternative and complementary medicine
- Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Lastly---let me know if this is too overwhelming for you, and I can do some more research for you (instead of listing journals)! I did not know how overloaded you wanted to be with information, and I can summarize what I find!
This is such a great question...I'm sure others will chime in as well!!
August 10, 2008 - 7:48pmThis Comment
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