I just turned 43 and thought that I was the only woman with these issues until I logged on here, so thank you to all of you for your comments. My migraines are killing me, it seems that three out of the four weeks in a month I am dealing with morning migraines that last all day. I know that I am in perimenopause because all the symptoms are there. I am going to see a gynecologist for some answers because being stupid, I haven't seen mine in awhile. My mother had breast cancer at age fifty and I wondered if I could still be placed on estrogen replacement due to her having had estrogen fed cancer. I did have a mammogram two years ago and am going for another soon, I wondered how a doctor determines if you have low estrogen and if a replacement would help my perimenopause and my migraines. Thank you for any help you can offer!