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I purchases Zicam Sunday for my sinuses are kicking my butt this winter. I'm glad I came to this web page when I typed in "zicam headache and stomache" for it suggested this site and I see all the responses to zicam. I have had a bad headache and my stomach has been upset. I must say it is helping my sinuses from dripping but I can't go on with my stomach and headaches. Sunday morning I did my nasal zicam and did it again Sunday night and I went to be around 10:30 and maybe got to sleep around 1am (not knowing what caused this). Monday I took some in the morning and had a headache and an upset stomach all day and didn't take any last night. I did squirt one time in each nostril today and I'm back to a stomach ache and headache..I'm done with Zicam..thanks for all the information I have read.