I took Pristiq for about a year and it made a huge improvement in my life. Then I moved to the UK, where it is not available, and have been suffering with medications that don't work for me. I believe it will help a lot of women, but you really must be honest about your symptoms and make sure you tell your doctor if you have suicidal thoughts or feel unwell. Depression and anxiety run in my mother's side of the family and there are a lot of us trying to find the right medication. I do believe it is inherited.