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Hi, Razldazlrr,

First of all, I'm so sorry you're feeling this way. You are right to inquire about whether you are on the correct dosage or the correct medicine for you -- we are all different in how we react to various anti-depressant medicines, and we have to sometimes work at it until we find what's working for us.

You should definitely not be feeling teary and sad all the time. That's a sign that the medicine is not working for you in some way. I would absolutely recommend that you call your doctor and let her or him know about how you're doing, and ask for some sort of change (either an increase or a different medicine).

If you have been taking 50 mg of Pristiq since December, that's been more than enough time for you to know how you react to it. Most anti-depressants are at their full strength in our bodies within a few weeks.

Did the Lexapro work for you? Or did it work for you and then stop working after a while? Can you tell me why the switch to Pristiq?

And have you had any other major changes in your life since December? Life changes, moves, extra stress, or other medication changes?

Do you drink alcohol at all? Even a glass of wine at night can affect the way some medications work in your body.

And may I ask how old you are? Sometimes medications affect people differently when they are either younger (late teens and early 20s) or older (40s and up) who are having changes in their hormonal levels.

Depression is tough. I have dealt with it myself, as well as medication changes. I know that on some days it's all you can do just to function. Please realize that that is the depression, not you.

Do call your doctor and make an appointment. From what you say, it sounds like this may not be working for you. There are many good medicines available and you absolutely should see if there are better options for you. And write back and let us know what happens, OK?

April 16, 2009 - 10:33am

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