I suffer from bipolar and depression. I own and have used both the Alpha Stim and the Fisher Wallace devices. Personally, and in my case ( everyone is different ), I find the Fisher Wallace device to be effective. I do a 40 minute session earlier in the day. I use the device on a lower setting. The Alpha Stim was effective for treating anxiety but did not have an effect on my depression. I highly recommend the Fisher Wallace device, but once again, everyone is different and it may not work for you. Since you will need a prescription to purchase the device, I strongly recommend you discuss this treatment modality with your physician.