The new study is a follow-up to a smaller 2011 study by Aronson and his team in which they found a low-fat diet with fish oil supplements eaten for four to six weeks prior to prostate removal slowed the growth of cancer cells in human prostate cancer tissue compared to a traditional, high-fat Western diet.
“These studies show that, in men with prostate cancer, you really are what you eat,” Aronson said in a press release. “The studies suggest that by altering the diet, we may favorably affect the biology of prostate cancer.”
In this study, funded by the National Institutes of Health, Aronson wanted to examine what potential biological mechanisms were at work in the low-fat fish oil diet that may be providing protection against prostate cancer growth and spread.
To do this, the researchers measured levels of the pro-inflammatory substances in the blood and examined the prostate cancer tissue to determine the CCP score.
Further, Aronson and his team analyzed one pro-inflammatory substance called leukotriene B4 (LTB4) and found that lower blood levels of LTB4 after the diet also coincided in lower CCP scores.
Now Aronson has been funded to start a prospective, randomized trial at UCLA in 2014 that aims to monitor slow-growing prostate cancer in 100 men using imaging and biopsy instead of treating the disease.
Lynette Summerill is an award-winning writer and Scuba enthusiast who lives in San Diego with her husband and two beach loving dogs. In addition to writing about cancer-related issues for EmpowHER, her work has been seen in publications internationally.
Men with Prostate Cancer Who Ate a Low-Fat Fish Oil Diet Showed Changes in their Cancer Tissue that May Help Prevent Disease Growth and Recurrence. UCLA Press Release, Kim Irwin. 18 Nov. 2013 and You are what you eat: Low-fat diet changes prostate cancer tissue. UCLA Newsroom News release. By Kim Irwin, 18 Nov. 2013.