Well if there are changes in the brain that explains why I get so forgetful. There are times when I am thinking about a certain word for days until it pops into my head and then I remember it. But while this is going on trying to remember, I start to become irritated and get upset at a drop of a hat. Now I do not know if this is related to brain changes or not. You know some times I get very bad pain in the head that it begins to cripple me. And that seems to occur if I am concentrating on one thing too long.