The short answer to your question is no.
Debridement is the surgical removal of foreign material or a person's dead, damaged or infected tissue from a wound or burn to prevent infection and promote healing.
Most blisters caused by friction or minor burns will resolve on without treatment. New skin will form underneath the affected area and the fluid is simply absorbed. The fluid-filled blister keeps the underlying skin clean, which prevents infection and promotes healing. If a fluid-filled blister must be popped, it is done with a sterile needle.