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Hello Anonymous,

Welcome to EmpowHER.

Are you asking about treatment of Hepatitis C?

In January 2016, the FDA gave approval to a once-daily pill combination of elbasvir and grazoprevir called Zepatier. It has been shown to have the ability to cure the disease in almost 100% of those treated. It follows the success of another once-daily treatment called Harvoni that cures the disease in most people in 8-12 weeks. Harvoni combines two drugs: sofosbuvir (Sovaldi) and ledipasvir. In clinical trials, the most common side effects in both drugs were fatigue and headache.

Other fairly

recent drugs are ombitasvir-paritaprevir-dasabuvir-ritonavir (Viekira Pak), ombitasvir-paritaprevir-ritonavir (Technivie) and daclastasvir (Daklinza) which do not require interferon and cure more people in less time. Ombitasvir-paritaprevir-dasabuvir-ritonavir and ombitasvir-paritaprevir-ritonavir carry an FDA warning of severe liver injury if given to someone with underlying severe liver disease. All of these medicines are quite expensive.

Instead, your doctor could recommend a combination of boceprevir (Victrelis), simeprevir (Olysio), sofosbuvir (Sovaldi), or ), or telaprevir (Incivek) with interferon (which you take by injection), and ribavirin (which comes as a liquid, tablet, or capsule).

Interferon and ribavirin used to be the main treatments for hepatitis C. They can have side effects like fatigue, flu-like symptoms, anemia, skin rash, mild anxiety, depression,nausea, and diarrhea.

Regards,
Maryann

July 4, 2017 - 12:19pm

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