Facebook Pixel
EmpowHER Guest

Has anyone had any side effects from hrt relating to the brain?

By Anonymous April 24, 2015 - 11:24am
Rate This

I had a total hysterectomy 6 years ago at age 37 from uterine cancer. I was put on HRT and have been in a fog and had trouble recalling thoughts or speaking without feeling like an idiot because I couldn't remember the words. Ialso had lack of appetite, didn't taste foods as well, and no desire to do anything. I decided to go off them this year cold turkey, and it's been 3 weeks and I feel great. All my social anxiety has gone away, I am out of the fog, I am getting a lot done and am soo extremely happy. I just want to know if I'm a rare case or if anyone out there has had issues with HRT affecting the brain and if so how?

Add a Comment3 Comments


Hi Anon,

It sounds like your case is different then most.  But again it all comes down to individuals, their hormone levels and personal experiences.  Ultimately, you did the right thing for yourself and I hope by sharing your question, someone in the community can learn not only from the common, but the uncommon.

April 27, 2015 - 4:42pm
EmpowHER Guest

Sorry Gillette, but what you are saying is that the menopause is what causes this brain "fog". And I have read too many articles about how HRT is the "cure" for these symptoms. I'm trying to find people who were normal before, but the HRT caused the problems, like not being able to taste food as well, not wanting to eat, feeling full after only a few bites, cognitive memory loss, feeling like a zombie all the time, not being able to have a proper conversation with someone because you can't think of what you are saying, social anxiety, feeling anxious or confused... I could go on, but all of these issues I've dealt with since being prescribed HRT 6 years ago and going off them only 3 weeks has cured me of all of these!

April 24, 2015 - 3:59pm

Hi Anon,


Thank you for sharing your question with  the EmpowHER community.

HRT (Hormone Replacement Therapy) is a treatment for menopause related symptoms given to women who's estrogen and progesterone levels have dropped significantly.  

Forgetfulness or "brain fog" are common complaints for women during menopause and there is even research suggesting that cognitive decline and memory problems associated with menopause may be linked to fluctuating levels of hormones in the brain. 

The above supports what you have been experiencing.   I'm not sure if your situation is rare, but I'm sure glad to hear that those undesirable symptoms have resolved and you are feeling much better. 

Here are some additional reading resources:

Get Rid of Brain Fog Once and For All

Menopause Symptoms: Dealing with Brain Fog

I hope this information was helpful.
Be well,
April 24, 2015 - 2:36pm
Enter the characters shown in the image.
By submitting this form, you agree to EmpowHER's terms of service and privacy policy
Add a Comment

All user-generated information on this site is the opinion of its author only and is not a substitute for medical advice or treatment for any medical conditions. Members and guests are responsible for their own posts and the potential consequences of those posts detailed in our Terms of Service.


Get Email Updates

Health Newsletter

Receive the latest and greatest in women's health and wellness from EmpowHER - for free!