Physicians who offer stem-cell face-lifts use a mechanical process to separate out stem cells from fat tissue, adding extra stem cells to injected fat. One such doctor claims, "The youthful glow comes back to skin because of growth factors that are produced from the stem cells." And that, in his opinion, doesn't happen by injecting fat alone.
The critics of stem cell facelift technique say that claims, such as 'youthful glow,' are not backed up by hard data but by patient anecdote. To get hard data, studies would have to be done in which, for example, one-half of the face was treated with traditional fat injections and the other with stem-cell-enriched fat. Then you would need ways to accurately measure skin changes. These studies would determine whether more facial volume is retained when you inject stem-cell enriched fat than unenriched fat.
In May 2011, a joint task force of the American Society for Aesthetic Plastic Surgery (ASAPS) and another leading plastic surgery society was formed to look into the scientific evidence assessing both the safety and efficacy of stem-cell use in aesthetic procedures. The task force urged caution on all aesthetic stem-cell procedures, and a hearty dose of "let the buyer beware." The report states "the marketing and promotion of stem cell procedures in aesthetic surgery is not adequately supported by clinical by evidence at this time."
However, there is tremendous potential for stem cells in aesthetic medicine. A prominent plastic surgeon says, "Stem cells in fat are very powerful releasers of growth factors that enhance tissue healing and can induce the growth of new blood vessels in the tissue." He is involved in a current clinical trial, financed by the National Institutes of Health, on the use of stem-cell-enhanced fat grafting versus nonenhanced fat grafting for treating facial deformities in wounded soldiers. The results of this trial will help boost or diminish the case for procedures like the stem-cell facelift.