Causes
Kidney, Ureter, Bladder, and Kidney Stone

Hydronephrosis is caused by two problems in the urinary system. A blockage may prevent urine from draining out of the kidneys. Or a condition called reflux may cause urine to flow back into the kidneys from the bladder.
Conditions that may cause hydronephrosis include:
- A blockage or defect in the urinary system that is present at birth
- Kidney stones
- A blood clot
- Scarring of the ureters (tubes that connect the kidneys to the bladder)
- A tumor in the pelvic area (such as bladder, cervix, colon, or prostate)
- Enlarged prostate
- Enlarged uterus during pregnancy
- Persistent urinary infection in the kidneys
- Neurogenic bladder
- Injury to structures in the urinary system (eg, from surgery or trauma)
Risk Factors
The following factors increase your chances of developing hydronephrosis:
- Defect in the urinary system that is present at birth
- Cancers in the pelvic area
- Pelvic surgery
- Blood-clotting disorders
- Recurrent urinary tract infections
- Enlarged prostate
- Neurogenic bladder
- Pregnancy
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