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Mellanie True Hills: Why Atrial Fibrillation May Be Missed More in Women

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We've long suspected that gender bias played a part in women not being diagnosed as quickly for heart disease as men, and a new study just presented at the Transcatheter Cardiovascular Therapeutics symposium appears to confirm that.

In the study, internists and family physicians were given a vignette to read and then diagnose and specify treatment. Vignettes were of a 47-year-old male and a 56-year-old female, with equal risk for heart disease and having a multitude of heart disease symptoms and risk factors. Half the vignettes included mentions of a recent life stressor and the appearance of anxiety.

When presented in the context of stress, there was a definite gender bias, with 15% of women receiving heart disease diagnosis compared to 56% of men, 30% of women receiving cardiologist referrals compared to 62% of men, and 13% of women receiving prescriptions for cardiac medication versus 47% of men. When stress wasn't mentioned, there was no evidence of bias.

The presence of stress shifted the interpretation of women's chest pain, shortness of breath and irregular heart rate to have a psychogenic origin [all in our heads], whereas men's symptoms were seen as organic [real] whether or not stressors were present.

Study authors said, "For women, the presence of stress or anxiety drives the interpretation of accompanying symptoms so that symptoms such as chest pain or shortness of breath undergo a 'meaning shift' when presented in the context of stress or anxiety and they are perceived as a manifestation of the stress or anxiety and not as CHD [heart disease] symptoms. For men, cardiac symptoms drive the interpretation of accompanying symptoms so that anxiety or stress is perceived (rightly so) as a risk factor for CHD and may in fact augment the CHD assessment. The presence of anxiety or stress in men does not deter from the CHD assessment; for women, it appears to preclude a CHD assessment."

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