Hepatitis B is a liver disease. It is caused by the hepatitis B virus. Most hepatitis B infections clear up within 1-2 months without treatment. When the infection lasts more than six months, it can develop into chronic hepatitis B, which can lead to:
- Chronic inflammation of the liver
- Cirrhosis]]> (scarring of the liver)
- ]]>Liver cancer]]>
- Liver failure
This virus is spread through contact with body fluids of an infected person. Fluids include:
- Vaginal fluids
The following situations may increase your risk of getting hepatitis B:
- Having sex with someone infected with hepatitis B or who is a carrier of hepatitis B
- Injecting illicit drugs, especially with shared needles
- Having more than one sexual partner
- Being a man who has sex with men
- Living in the same house with someone who is infected with hepatitis B
Having a job that involves contact with body fluids, such as:
- First aid or emergency workers
- Funeral directors
- Medical personnel
- Dental assistants
- Police personnel
- Having a sexually transmitted disease at the time you come in contact with hepatitis B
- Traveling to areas where hepatitis B is common, such as China, southeast Asia, and sub-Saharan Africa
- Receiving a blood transfusion prior to 1992 (the year a more reliable test to screen blood was developed)
- Receiving multiple transfusions of blood or blood products, as hemophiliacs do (risk is greatly reduced with modern blood screening techniques)
- Working or being a patient in a hospital or long-term care facility
- Working or being incarcerated in a prison
- Being bitten so that the skin is broken by someone whose saliva contains the virus
- Receiving hemodialysis treatment
These may appear about 25–180 days after you are exposed to the virus. The most common symptoms are:
- Yellowing skin and eyes ( jaundice]]> )
- Fatigue that lasts for weeks or even months
- Abdominal pain in the area of the liver (upper right side)
- Loss of appetite
- Joint pain
- Low-grade fever
- Dark urine and light-colored stool
- Widespread itching
The doctor will ask about your symptoms and medical history. A physical exam will be done. Hepatitis B is diagnosed with blood tests. These blood tests are also used to monitor its effects on the liver.
For chronic cases, a liver biopsy]]> may be needed. A biopsy is the removal of a sample of liver tissue for testing.
The symptoms can be treated with medication. If you have an uncomplicated case, you can expect to recover completely.
If you have chronic hepatitis B, you may be treated with medication. This will help to reduce the activity of the virus. It can also prevent liver failure.
- Interferon alfa-2b]]> (Intron A) injection
- ]]>Lamivudine]]> (Epivir-HBV) oral medication
- ]]>Adefovir]]> (Hepsera) oral medication
- ]]>Entecavir]]> (Baraclude) oral medication
If you have chronic hepatitis B, you should avoid anything that can further injure the liver, including:
- Certain medications, dietary supplements, and herbs (discuss them with your doctor before taking)
If you have chronic hepatitis B, prevent the spread of the infection by:
- Telling your doctors, dentists, and sexual partner(s) that you have hepatitis B
- Never donate blood, organs, or tissue
- Discussing your hepatitis B status with your doctor during pregnancy or before becoming pregnant to insure the baby receives treatment
Hepatitis B can be prevented with a vaccination]]> . It consists of three injections. They are given over six months. Protection is not complete without all three. Anyone at increased risk for hepatitis B should be vaccinated.
In addition, to prevent the transmission of hepatitis B:
- Use condoms or abstain from sex.
- Limit your number of sexual partners.
- Do not inject drugs. If you use IV drugs, get treatment to help you stop. Never share needles or syringes.
Do not share personal items that might have blood on them, such as:
- Manicuring tools
- Pierced earrings
- If you get a tattoo or body piercing, make sure the artist or piercer properly sterilizes the equipment. You might get infected if the tools have someone else's blood on them.
If you are a healthcare or public safety worker:
- Get vaccinated against hepatitis B.
- Always follow routine barrier precautions and safely handle needles and other sharp instruments.
Wear gloves when touching or cleaning up body fluids on personal items, such as:
- Cover open cuts or wounds.
- Use only sterilized needles for drug injections, blood testing, ear piercing, and tattooing.
- If you are pregnant, have a blood test for hepatitis B. Infants born to mothers with hepatitis B should be treated within 12 hours after birth.
American Liver Foundation
Hepatitis B Foundation
Canadian Institute for Health Information
Canadian Liver Foundation
American Liver Foundation website. Available at: http://www.liverfoundation.org .
Braunwald E, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Longo DL, eds. Harrison's Principles of Internal Medicine. 15th ed. McGraw-Hill; 2001.
Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/ .
Last reviewed January 2009 by ]]>David L. Horn, MD, FACP]]>
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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