What Is Purine?
Purine is a compound found primarily in foods of animal origin. It is especially high in organ meats, anchovies, mackerel, and sardines.
Why Should I Follow a Low-Purine Diet?
The body metabolizes purine into uric acid. A buildup of uric acid can worsen symptoms of gout. If you have gout, eating a low-purine diet can help minimize uric acid production and thereby improve symptoms.
Eating Guide for a Low-Purine Diet
|Food Category||Foods Recommended||Foods to Limit or Avoid|
|Meat and Beans|
In addition to following a low-purine diet, here are some other suggestions for decreasing uric acid production:
- Avoid or limit your intake of alcohol, especially beer. While alcohol does not contain purines, it increases your production of purine.
- Drink 8-12 cups of fluid every day. This will help dilute your urinary uric acid, which can help prevent kidney stones from forming.
- Consume low-fat or nonfat dairy products, such as milk and yogurt, on a regular basis. Research shows that these foods may help prevent gout from occurring.
- Limit your intake of fat to 30% of your calories.
- Don’t follow low-carbohydrate diets.
- Avoid rapid weight loss, as this can increase your uric acid levels. If you need to lose weight, do so gradually.
- Consider meeting with a registered dietitian to come up with a personalized eating plan.
The Arthritis Foundation
The Purine Research Society
The Arthritis Society
Dietitians of Canada
Choi HK, Liu S, Curhan G. Intake of purine-rich foods, protein, and dairy products and relationship to serum levels of uric acid: the Third National Health and Nutrition Examination Survey. Arthritis Rheum. 2005;52:283-289.
Fam AG. Gout: excess calories, purines, and alcohol intake and beyond. Response to a urate-lowering diet. J Rheumatol. 2005;32:903-905.
Gout: is a purine-restricted diet still recommended? American Dietetic Association website. Available at: http://www.eatright.org/cps/rde/xchg/ada/hs.xsl/nutrition_5314_ENU_HTML.htm . Accessed June 22, 2007.
Hyon CK, Mount DB, Reginato AM. Pathogenesis of gout. Ann Intern Med. 2005;143:499-516.
Low-purine diet. University of Pittsburgh Medical Center website. Available at: http://patienteducation.upmc.com/Pdf/LowPurineDiet.PDF . Accessed June 21, 2007.
Nutrition care manual. American Dietetic Association website. Available at: http://nutritioncaremanual.org/auth.cfm?p=%2Findex.cfm%3F. Accessed January 3, 2009.
Last reviewed January 2010 by ]]>Maria Adams, MS, MPH, RD]]>
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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