St. Louis Encephalitis
Definition
St. Louis encephalitis is a viral disease spread by infected mosquitoes. This disease can affect the central nervous system, causing severe complications and even death. The virus was discovered in 1933. It is estimated to have been reported in 10,000 cases of illness and 1,000 deaths.
The Central Nervous System

Causes
St. Louis encephalitis is caused by a virus with the same name. Mosquitoes are infected with this virus when they feed on birds, and infected mosquitoes can transmit the virus to humans and animals. St. Louis encephalitis is not spread from person to person.
Risk Factors
A risk factor is something that increases your chance of getting a disease or condition.
Some factors thought to increase the risk of St. Louis encephalitis include:
- Elderly age
- Living in or visiting the southern, central, or western United States, especially during the summer and fall
Symptoms
St. Louis encephalitis can result in a wide range of symptoms, or produce no symptoms at all. The disease can be mild, severe, or even fatal. The disease is fatal in 3%-30% of people who develop symptoms. Symptoms associated with St. Louis encephalitis usually appear 5-15 days after the bite of an infected mosquito and may include:
Diagnosis
Your doctor will ask about your symptoms and medical history, and perform a physical exam. He or she will also perform blood tests to identify the virus.
Treatment
There is no specific treatment for St. Louis encephalitis. Treatment will focus on managing your symptoms and related complications.
Prevention
There is no vaccine against St. Louis encephalitis. Prevention of this disease centers around controlling mosquitoes and avoiding mosquito bites. Steps you can take to avoid mosquitoes include:
- Stay inside between dusk and dark. This is when mosquitoes are most active.
- Wear long pants and long-sleeved shirts when outside.
- Spray exposed skin with an insect repellent that contains up to 35% diethyltoluamide (DEET).
RESOURCES:
Centers for Disease Control and Prevention
http://www.cdc.gov
National Library of Medicine
http://www.nlm.nih.gov/
CANADIAN RESOURCES:
Canadian Centers for Occupational Health and Safety
http://www.ccohs.ca
Public Health Agency of Canada
http://www.phac-aspc.gc.ca
References:
CDC answers your questions about St. Louis encephalitis. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/ncidod/dvbid/arbor/SLE_QA.htm . Accessed July 4, 2007.
St. Louis encephalitis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Accessed July 4, 2007.
Last reviewed November 2008 by David L. Horn, MD, FACP
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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