Have I ever mentioned that I hate shots? I don’t mean that I dislike them. I mean that I really, really have this thing about needles as it relates to being in the same vicinity as my body. I’ve always hated the pat little half-smile, as the nurse says, “Now, honey, you’re going to feel a little sting.” Yeah, right. Sting my @@)#$*&!!!
Despite my intense dislike of needles, I self-administer a shot every day. Why, you may ask? Because I have multiple sclerosis and all the major hitters in terms of MS treatments – Avonex, Beta Seron, Rebif and Copaxone – are all injection medications only. Other MS treatments involve intravenous infusions (again, a needle). There is currently no treatment available for MS in pill format. So, a girl does what a girl has to do. I’ve sucked it up and every evening for the past 9 and a half years I’ve had a “date” with the needle. Believe me, he’s not a date I like to keep and I can’t wait to send him packing!
For all of us needle phobia MS sufferers, injections may soon be a thing of the past. Hope just may be on the not-so-distant horizon. The results of the Cladribine Tablets Treating MS Orally (CLARITY) trial were released earlier this year. If approved by the FDA, Cladribine will be the FIRST oral medication approved for the treatment of MS. (Yeah! No more needles!)
The short and skinny on the trial results are as follows:
• Course of treatment: Participants were given either two or four courses of treatment each year during the trial. A course of treatment consisted of a single pill for a period of four to five days. That means that even with a four-course treatment during the year, you’re only looking at 20 pills a year.
• Relapse Prevention: Participants were 58 percent less likely to suffer a relapse. (Yes, I said 58 percent!)
• Progression of Disease: Participants MS disabilities were 30 percent less likely to worsen than those on placebo.
• Lead Researcher: Professor Gavin Giovannoni of Barts and The London School of Medicine and Dentistry, part of Queen Mary, University of London
• Manufacturer: Merck Serono (Geneva, Switzerland)