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How could I have a normal Pap one week before being diagnosed with Cervical Dysplasia?

By February 2, 2011 - 3:57pm
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I was having pain with intercourse and frequent bladder infections and went to my OB/GYN. She did a Pap (which was normal) and a physical exam. A week later I had a colcoscopy and a cone biopsy showing precancerous cells. I was then tested for HPV and was negative.
I thought that HPV always caused Cervical Dysplasia, so why am I negative? Why didn't my Pap show the abnormal cells one week before?
My doctor suggested a LEEP, but indicated that it will increase the chance of miscarrage if you get pregnant within 2-3 years of having the proceedure, as the cervix is not fully healed right away.

My other option is to have more frequent Paps and watch it, but my last Pap was negative so I question if changes in the condition will show up on a Pap.
I used Depo shots for the last year or so (stopped 3 months ago) and wondered if they could have caused the Cervical Dysplasia. I have not yet had a period since stopping the shots.
I am getting married and hope to start a family soon. What happens if I am pregnant and the Cervical Dysplasia progresses to cancer?

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Expert HERWriter Guide Blogger

CSR1983 - Thank you for sharing your situation and seeking information to support your health.

First, it's hard to know why your pap test didn't pick up the cervical dysplasia, it should have.

While most cases of cervical dysplasia and cervical cancer involve HPV, it is not the only cause. The following have been shown to increase a woman's risk of cervical cancer.
* Becoming sexually active before age 18
* Giving birth before age 16
* Having multiple sexual partners
* Having other illnesses or using medications that suppress your immune system
* Smoking

In terms of a possible relationship between Depo Provera and cervical dysplasia, please see the following thread: https://www.empowher.com/community/ask/can-depo-provera-shot-cause-cervical-dysplasia

Cervical cancer is a slow-growing and highly treatable cancer. It can take 10 years or longer for cervical dysplasia to develop into cancer. As long as you have regular check ups and medical care, you can be on top of your risk for this cancer.

You can find more information about cervical dysplasia, tests, cancer and more at the following link: http://www.nlm.nih.gov/medlineplus/cervicalcancer.html

Please let me know if I can help further.
Take care,

February 2, 2011 - 5:51pm
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