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Hello. Thank you for writing.
Most drugs, particularly water-soluble drugs and their metabolites, are eliminated largely by the kidneys in urine. Therefore, drug dosing depends largely on kidney function. Some drugs are eliminated by excretion in the bile (a greenish-yellow fluid secreted by the liver and stored in the gallbladder). Your pharmacist may be able to give you more specific information.
Helena
June 8, 2018 - 6:29pmThis Comment