Definition

Sickle cell anemia is a genetic disorder. It alters the shape of the red blood cells (RBCs). This decreases their ability to carry oxygen. It can also cause acute episodes of pain. These are called a sickle cell crisis. The body will also destroy the sickle cells. The loss of RBCs results in anemia .

The change in the ability and number of RBCs can decrease the amount of oxygen for the body.

Red Blood Cells: Normal and Sickled

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