There are several new thyroid hormone preparations that can be used to treat patients with hypothyroidism. These include a new preparation of levothyroxine called Tirosint that is the only thyroid preparation in a gel capsule. There is also a new preparation of desiccated thyroid (from porcine thyroid) called WP thyroid, that is similar to Nature-Throid.
Many patients have trouble absorbing standard thyroid preparations such as levothyroxine, Synthroid or Levoxyl. Certain conditions and several medications (calcium, iron, vitamins that contain calcium and iron, and antacids or proton-pump inhibitors) affect absorption of levothyroxine that can lead to variable thyroid levels with resultant symptoms of hypothyroidism.
Alternatively, if the absorption was affected and then the condition improved or the medication was discontinued or taken separately from the thyroid medication, symptoms of hyperthyroidism can occur.
An acidic stomach is needed to optimally absorb thyroid medications, so antacids and protein pump inhibitors (PPIs, Prilosec, omperazole) can affect absorption. Conditions such as pernicious anemia, lactose intolerance, untreated celiac disease and gluten intolerance can also affect thyroid hormone absorption.
The new thyroid hormone compound Tirosint contains levothyroxine in a gel form with very little fillers or binders and comes in 10 doses (13 mcg, 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg).
It doesn't require an acidic stomach, so it can be used in patients on antacids and PPIs, and in those with pernicious anemia, lactose intolerance, untreated celiac disease and gluten intolerance.
Tirosint is made in a dedicated production facility that means that no other products are produced in the same location. This eliminates the possibility of Tirosint becoming exposed to ingredients that may be used in the production of other medicines.
For people with serious food allergies or food restrictions, exposure to event minute quantities of certain ingredients may cause a severe reaction.
Tirosint comes packaged in a color-coded blister pack to indicate its strength.