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5 Things to Know About the C. Difficile Bacterial Infection

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People who are familiar with it give it the nickname “C-diff.” But the informality of that name belies the seriousness of the condition, properly known as a Clostridium difficile infection. And if the infection is not treated with haste, it can be deadly.

It’s been in the news lately because of fears that the overuse of antibiotics has turned C-diff into a “superbug,” a strain that defies standard germ-fighting practices.

But before anyone jumps to the conclusion that fighting C. difficile is a lost cause, here are five things to know about this scary form of bacteria:

1. It often hits patients in hospitals, nursing homes and other health care settings who have been taking antibiotics. It is spread through feces, which means health care workers need to be extremely careful about wearing gloves when dealing with anything having to do with bathroom use.

2. A C. difficile infection can cause moderate to severe diarrhea, fever, nausea, loss of appetite, abdominal pain and, in some cases, colitis. It can be fatal, but that is rare. Also, it is possible to have C. difficile in your system yet show no symptoms.

3. Discontinuing use of the patient’s current antibiotics will resolve the symptoms in about 20 percent of patients, according to the Centers for Disease Control and Prevention (CDC). Doctors may prescribe a course of new antibiotics, usually metronidazole or vancomycin.

4. Although C. difficile infection is mostly seen in elderly patients, the CDC has reported seeing more instances outside nursing homes and hospitals over the past several years. Also, states across the country have reported more cases of C. difficile infection, more severe symptoms and an increase in related deaths. The CDC said the reasons could include: changes in antibiotics use, changes in infection control practices, or the emergence of a strain that resists eradication.

5. The overuse of antibiotics comes into play because many of today’s broad-spectrum antibiotics kill the bacteria in our intestines that normally would be able to fight off C. difficile germs.

Other important points:

People who are “overtreated” with antibiotics are more likely to be hit with C. difficile infection, according to an April 14, 2009, article in The New York Times. The illness kills an estimated 15,000 to 20,000 people a year, the article noted.

Even though C. difficile infections appear to be on the rise, the information is out there on how to guard against it with proper hygiene. In addition, doctors are having success in treating it; a new antibiotic called fidaxomicin shows promise and is being reviewed by the U.S. Food and Drug Administration. And studies show that the risks of catching C. difficile infection outside a hospital or nursing home setting are still low, at about seven out of every 100,000 cases.



Reviewed May 23, 2011
Edited by Alison Stanton

Deborah Ross writes about health, education, the arts and Arizona travel from her home in Phoenix.

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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

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