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Genetic Tests Detect Thyroid Cancer Without Surgery

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Thyroid Conditions related image Photo: Getty Images

Each year, tens of thousands of people undergo unnecessary thyroid surgeries to remove part or the entire hormone gland after doctors discover suspicious nodules. He or she then faces a tense waiting period to see if, over time, clear signs of cancer develop.

But what if a test could analyze cell samples in a laboratory to determine with a high degree of certainty if cancer is present? If genomic markers coded in cells could signal doctors that a tumor is benign, many patients could avoid the unnecessary trauma, cost, discomfort and risk of surgery.

Welcome to the future.

Doctors at the University of Colorado School of Medicine are helping to pioneer this revolutionary genomic approach that only a few months ago was unavailable to thyroid patients. It is being successfully used at limited sites around the country, but could be coming to a hospital near you next year.

Dr. Bryan Haugen, MD, who heads the Division of Endocrinology, Metabolism and Diabetes at the CU medical schools says usually cells extracted from suspicious nodules in the thyroid are benign, but in 15 to 30 percent of those samples it’s simply hard to tell.

The next step requires surgeons to remove all or part of the thyroid for further testing. The good news is about 70 percent of the time, no cancer is present. The bad news is the patient is unnecessarily subjected to surgery and lifelong thyroid hormone treatments.

The thyroid is a butterfly-shaped gland located in the front of your neck that produces hormones that controls your metabolism speed. Unexplained weight gain, swelling or enlargement in the neck— called nodules, high blood pressure and heart palpitations, tiredness, depression and difficulty sleeping, hair loss, and numbness or tingling in the hands can all be symptoms of a thyroid disorder.

Haugen is part of a national team who sought an alternative to surgery to determine if cancer was present in those hard-to-tell cell samples. It turns out all the information doctors need is coded in a person’s genes.

Add a Comment3 Comments

EmpowHER Guest

I had a biopsy in 2002,came back suspicious. had another biopsy 2012 came back non cancer.I do not know what to do? Please help.

January 29, 2012 - 12:23pm

Thank you for your post Anon. Please consider sharing more about your experience with this surgery and your life post-surgery. What advice would you have for anyone facing this sort of surgery? Thanks again.

December 21, 2010 - 7:48am
EmpowHER Guest

There are many unwanted effects to having a Total or partial thyroidectomy . I gave birth to my son three weeks before I had a complete done and my entire life has not been the same ever since. There are good days and there can be harmful days. Maintaining on the medication levels is important.

December 20, 2010 - 10:44pm
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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

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