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I had the pellets inserted one month ago and have had bad headaches, difficulty sleeping, the arousal a week ago was getting to the point of insanity and then I started my period. I'm 60 and haven't had a period in ten years. When I called the doctor they only asked if I was taking the prometrium as prescribed which I am. The doctor asked for new blood work which I'm doing today. The good news is that I have more energy and seem to be happier but there are definite side effects to this natural way of dealing with menopause.