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DON’T CONFUSE PURE FRUCTOSE WITH SUGAR OR HIGH FRUCTOSE CORN SYRUP.

The posting from Dr. Daemon Jones makes a common, but unfortunate, mistake by treating High Fructose Corn Syrup and fructose as though they are identical….they are not.

Fructose is, as the name implies, 100% fructose. High Fructose Corn Syrup is essentially half fructose and half glucose just like sugar. A better comparison for HFCS would be with table sugar (sucrose) which is what it is designed to replace in the human diet. Studies in my research laboratory and others have shown that by every parameter yet measured in human beings including insulin, leptin, ghrelin, blood sugar, uric acid, triglycerides, appetite and calories consumed at a subsequent meal High Fructose Corn Syrup and table sugar (sucrose) are identical.

There is no evidence whatsoever that High Fructose Corn Syrup creates any unique metabolic abnormalities, despite the assertions that Dr. Jones makes. In fact, there is overwhelming scientific agreement to the contrary, namely that High Fructose Corn Syrup and sucrose are metabolized the same, have the same sweetness, have the same calories per gram and may be consumed in moderation without causing metabolic abnormalities. The American Medical Association studied HFCS for a year and found that there was no unique relationship to High Fructose Corn Syrup and obesity. Research in my laboratory has also shown that High Fructose Corn Syrup does not cause either insulin resistance or excessive fat storage.

It is time for those of us in the scientific community to stop confusing the public by mischaracterizing High Fructose Corn Syrup as though it is the same as pure fructose. The comparison of HFCS and sucrose (table sugar) is the correct comparison and in this real world setting there are no metabolic abnormalities based on moderate consumption of either.

James M. Rippe, M.D.

June 25, 2009 - 11:39am

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