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"That's the paradox," Melvin Rosenwasser, chief of orthopedic trauma surgery at Columbia University Medical Center in New York, told USA Today.

I'm not sure why this is such a paradox to the chief of ortho trauma. Its a simple inventory issue. Think of a women's bones as an inventory supply of bone cells moving in and out of the "warehouse" (bones)

These women present with more old bone cell going out than they have new bone cell coming in.....so they take Fosamax and "freeze the inventory". Then it seems like its working great for a good five-ten years before all of the "inventory" is way beyond its fresh date and essentially worthless.

Why is anyone in the medical community surprised? Paradox my foot. It is the simple, predictable outcome of the basic mechanism of the drug. All this talk about how much good the drug does is just so much vacant thinking and flumdiddle. If I stop paying my mortgage, its great for a while, then it gets worse, then they take my house away.

Now that Iknow the mechanism of action of these drugs, l wonder what kind of moron at the FDA wouldn't ask the question "what happens went the rent comes due on that mechanism of action?"

March 25, 2010 - 7:57pm

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