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Thank you for the article---that was interesting.

However, this is exactly what the doctor prescribed, and it was found successful in women "with less-severe symptoms". What are your thoughts on this paragraph, from your article:

"The GnRH agonist, leuprolide acetate, has also been found to be effective in treating premenstrual mood disturbances. Brown et al. (10) administered the depot leuprolide intramuscularly for three consecutively cycles in 25 women with late luteal dysphoric disorder. Depot leuprolide was ineffective for women with severe premenstrual depression and associated with adverse events. For women with less-severe symptoms, depot leuprolide was well-tolerated and effective in reducing symptoms. The authors speculated that severity of symptoms may be indicative of diagnostic subtypes; women with severe premenstrual depression may have a more sensitive hypothalamic-pituitary-ovarian feedback system. "

I do not want to suggest that I am encouraging you toward one treatment or another; I am just curious why your doctor suggested one treatment (that has shown effective, in your article), but you are not wanting to try it?

February 13, 2011 - 9:27pm

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