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ask: How long should antibiotic-related intestinal side effects last once the medicine is done?

By Nancy Drew Fan
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Okay, I'll try to make this post as "non-TMI" as possible. I had my first-ever sinus infection a few weeks ago, and the PA at my doctor's office prescribed Omnicef for me for 10 days. It did a great job at knocking out the cooties and making me feel better, but it's also wreaked havoc on my intestinal system. About halfway into the 10 days I started getting diarrhea, sometimes as much as 8 times a day. Fun stuff, huh?

I figured the trots would improve when the Omnicef was done, but they kept going. About 5 days after finishing the Omnicef I asked the pharmacist how long I could expect the diarrhea side effects and she so obviously guessed when she said "oh I'm not sure, but I'd say about a week or so, I would think" Don't you love it when they make stuff up on the spot?

So now it's been 9 days since I've had my last Omnicef pill and I'm still having mild symptoms. Not "oh man, get me to the bathroom NOW" symptoms, but things just aren't 100% yet. I've bought some strong acidophilus and am taking it 3 times a day and am trying to eat more good-quality plain yogurt. TMI alert--there is just a lot of mucousy reddish brown stuff coming out and it's creeping me out. I read that Omnicef can cause reddish poos due to the way it interacts with iron in your diet, but would this still be the cause a week-plus after finishing the dose?

Does anyone know how long antibiotics essentially stay in your system, and how long I have to put up with this? It's getting better overall but it seems like this might be a medicine I want to avoid in the future. At what point do I call the doctor for a follow-up? thanks to everyone and I hope I didn't gross anyone out too badly.

Add a Comment40 Comments

EmpowHER Guest

I took Ciprodex 500 for 2.5 days (5 tabs in total) and had such a severe reaction I actually went to my local emergency. I was feeling terribly nauseated, noticed my heart rate slowing down (which was really scary), no energy and abdominal discomfort. I've never felt like that on antibiotics. The hospital ran general blood tests, an EKG and an x-ray, all which came up negative (which is good but begs the question if they were actually the right tests at all to determine if I experienced some form of reaction to the drug). I haven't taken the drug now for 5 days and am feeling pretty awful. Nauseated, dizzy, weird feeling in my throat and abdominal discomfort not to mention no energy to do anything but lie in bed. This drug is hazardous. Does anyone know how long it would take for the side effects to subside? Any other recommendations to speed the healing process?? Many thanks.

September 28, 2014 - 9:19am
EmpowHER Guest

You could have antibiotic induced colitis. If so it will not clear up until you get a different medication to treat that. If you are having to use the bathroom many times per day you need to see a doctor.

July 26, 2014 - 6:13am
EmpowHER Guest

The only thing that has really helped is ' time '..... I was the one who suggested ginger cookies, and they helped, but as time goes on it does improve but I've started eating a yogurt daily to get the probiotics (the good gut stuff that kills off the bad in your stomach ). It really helps with the odd bouts of nausea that I still feel now and then, but my stomach is just about back to normal. I used Activia yogurt , I think it works !!! You can also get probiotic tablets if you don't like yogurt, but I'm not sure they did as much good. Hope you get to feeling better. I also realized I'm under a lot of stress too, so I'm probably not helping myself to get better quickly.

July 3, 2014 - 6:45am
EmpowHER Guest

Applying castor oil on the tummy( externally) can cure you completely of this problem.

Please do note: apply externally only.
Good Luck
Sonali Patel

July 3, 2014 - 6:23am
EmpowHER Guest

Try eating ginger biscuits/cookies. Ginger is a stomach calmer/healer and was very big in England. They helped my nausea and diarreah a lot !

June 12, 2014 - 8:40am
EmpowHER Guest

i was taking cipro and flagly for ibs colitis how long does it take to get the drugs out of my system they make me feel sick and can not sleep well at all few hours a ady most

September 25, 2013 - 9:21am
EmpowHER Guest
Anonymous (reply to Anonymous)

I read your comment about Cipro. I just finished the last of a Cipro prescription last night and this morning I am so nauseated. And I have not had a good night's sleep the whole time I took it. How long did it take for your nausea and other symptoms to go away after you were done with the mediation? Thanks sooo much cause I never am nauseated or vomit and this is really miserable.

August 18, 2014 - 7:28am
EmpowHER Guest
Anonymous (reply to Anonymous)

Hi, I just wondered if your nausea/vomiting has gone away yet? I started reacting to Cipro on Sunday night after taking it for 5 days and I was told to stop the tablets. Since then I have just got worse, I feel nauseated all of the time, and I am sick every morning when i wake up. I also have this burning pain across the top of my back and shoulders and have absolutely no energy. Today is day 4 after stopping Cipro and I just seem to be getting worse. I am hoping you will tell me your nausea has now improved and give me some hope! I hope you feel better very soon.

August 28, 2014 - 2:49am
EmpowHER Guest

I found this site after searching in google and this exactly matches my symptoms, I have been taking Clindamycin for a skin related infection and also doctor gave me a shot of CEFTRIAXONE the first day since he saw puzz coming out as well. From that day i have been experiencing diarrhea for 4-5 times and the doctor prescribed Doxycycline as an alternative to Clindamycin.
Now i do not have the feeling of Got to go but whenever i go i have been experiencing Loose Stools (Watery, Green to brownish) from the past 12 days.

I have stopped taking the Antibiotics for the past 5 days. But my doctor wanted to take the Stool test as well. Hopefully this goes away in 3 days.

May 6, 2013 - 4:17am
EmpowHER Guest

I don't have intestine problems before and I could eat anything without any trouble. I've also taken antibiotics before, 2-3 weeks at a time and just have mild stomach upset...nothing to complain about at all.

Then after THE surgery a month ago , and I'm sure alot of antibiotics intraveneously, and I am having (just in the mornings..about 3-4 hours) loose BM or formed BM that breaks up when flushed followed by cramps and then another movement and follow by more cramps. 80% of the time, the BM has particles...like I'm not disgesting all the food and actually see tomatoes and bell peppers (sorry!). I only have gas in the morning intially, but just the last few days, getting gas in the evening...so I'm hopeful that I'm getting back to normal ? (please!!!) . I can't confidently get out of the house until about 4 hours after I wake. Very disturbing and depressing. Is loose BM the same as diarrhea? I've got cramps like D but it's not waterly or noisy (sorry, gotta mention that).

I called the DR and he suggested Immodium AD. It's still the same...formed but breaks up later. I called to ask how long am I supposed to take Immodium...cuz the box says it should take care of it in 2 days...and it's been 2 days and still loose...but he didn't even have the courtesy to call back !

Tried probiotics for more than a week already. All the sites that I've visited just have complaints like mine but I have yet to read that someone actually got better. That is very hopeless because I'm thinking that this is how my life will be from this surgery forward. I'm soooooooo sad. Since the DR didn't call back, I think he's ignoring the fact that I have a very serious problem with my gut or he just knows that there's no solution. Wish they never gave me the antibiotics and just wait a few days to see if I need it. Just want to whine....

October 4, 2012 - 10:22am
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