Sarcoidosis: Current Research
Sarcoidosis is an inflammatory disease characterized by small nodules (granulomas) of immune cells. The granulomas can occur in virtually any organ, but the lungs are the predominant site. Sarcoidosis looks similar to tuberculosis, some fungal infections, and chronic beryllium disease. These possibilities must be ruled out before sarcoidosis is diagnosed. About 1.3% of women will experience sarcoidosis sometime in their lives. The majority of cases last 12 – 36 months, while more serious cases persist for up to 5 years, and a few last for decades.
The cause of sarcoidosis is not well understood. Various antigens are thought to trigger an exaggerated immune response in genetically susceptible individuals. Young and middle-aged adults are most at risk. A recent study at the University of Pennsylvania identified mold, musty odors, and insecticides as environmental factors that may trigger the disease. A research team in Belgium reported that interferon, used to treat conditions including hepatitis C, induces the development of several immune diseases, including sarcoidosis.
The main treatment option is corticosteroids.
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Hi Linda - Thanks for this comprehensive overview of sarcoidosis, a disease which is not frequently covered in mainsteam media sources. I know your information is going to prove helpful to those with sarcoidosis, as well as family members and friends.
Take good care,
Pat