Nicotine Patch Plus Lozenges Can Help Discontinue Smoking, Studay Says Part 1
Many therapies for discontinuing smoking exist but most do not work. Now the latest study from the University of Wisconsin indicates that a combination of nicotine patch plus lozenge almost doubles the rate of abstinence at 6 months compared with placebo.
One of the authors of the study, Megan Piper, Center for Tobacco Research and Intervention, School of Medicine and Public Health, says "This is the first time that a head-to-head study has been done looking at all the different smoking cessation pharmacotherapies, and it's also one of the first times that combination therapies have been looked at in a large sample. When you get a 40% quit rate at 6 months in a group, that's really promising for smokers who are trying so hard to quit."
The study looked at 1504 adults who smoked an average of 10 or more cigarettes a day for at least the past 6 months and were randomly assigned to 1 of 6 treatments:
• bupropion SR (Zyban), 150 mg twice
• nicotine lozenge (2 or 4 mg)
• nicotine patch (24-hour, 21, 14, and 7 mg);
• nicotine patch plus nicotine lozenge;
• bupropion SR plus nicotine lozenge;
• placebo
All the participants also received six 10- to 20-minute individual counseling sessions.
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