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can mania be triggered by pmdd or pms???

By Anonymous May 6, 2011 - 11:54pm
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Menstrual psychosis: Can mania be triggered by pmdd or pms?

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I have been misdiagnosed as bipolar 3 and am searching for information and answers. 4 years ago I had a manic episode that happened on the same week as my period. 4 or 5 weeks of medication and treatment got me back to work and health. I gradually stopped the medication and have not needed it for the past 4years until last week. Since then I have not had a "real" period in 4 years (i say this because i normally have long and heavy periods). Mainly due to birth control pills, pregnancy, and breastfeeding my cycle did not return. But 2 weeks ago I had my first period in four years and later that day had a manic episode that I am still trying to recover from. What is going on? How could I be fine for 4 years with no meds and then POW my period and craziness???

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EmpowHER Guest

I have PMDD and have had 2 manic episodes with psychosis symptoms triggered by it. One in January 2017 and the other in late March early April 2017. My nurse and doctor both agree that that caused it because they saw me regress the in May 2017 the week before my period. I was getting better and better then I steadily started to spin again (I have rapid cycling with mixed states). It's hard to describe the spin but anyone who has seen me from no mania to the height of mania knows not how to describe the term but that it makes perfect sense.

June 2, 2017 - 4:15pm
EmpowHER Guest

I had very regular PMS all of my life until I had a hysterectomy/oophorectomy when I was 36 years old. I hated all the symptoms except for the mania I experienced once each cycle, just before ovulation. I loved this day, in fact, I used this day to get things done, take tests. I loved how this made me feel and always thought if I could bottle it, I could make a fortune. The problem was, if it went on for more than a day or two, I could have been in trouble because I felt as if I could conquer the world, it was a true mania. I have always wanted to know what hormone caused this because if had many beneficial effects and would have liked to replicate the side effects in a controlled manner. If there is anyone that knows what causes this I would love if you would share this with me.

July 1, 2014 - 5:43am
EmpowHER Guest

I found myself here because I have noticed a "manic" tendency I have that seems to line up around the time I ovulate. I am interested in finding out if there is any info out there about a connection between ovulation and mania. The only tid bit of info I read was this one thing.... somewhere on line... where it was listing common symptoms of ovulation and it listed "a boost in energy" which made me feel a little bit better, knowing that I was normal in that, but still.. a "boost in energy" hardly comes close to the type of energy I feel when I ovulate. It's not even just "energy", I mean... it is... but it's also a little manic, as I said. I am not "bipolar" btw. I have other psych issues that I see a psychiatrist for, but he has said many times that he does not see me as bipolar. I found this sort of disheartening, because I was seeking a reason for my cyclical manic episodes and until this last month I didn't think I had one, but I figured out, they line up w/ when I ovulate. This last one lined up EXACTLY. Ive been going back in my journals and using an online ovulation calculator. It's fucking insane. I had no idea. I seriously feel like I'm onto something here. I'm actually really excited to tell my Psychiatrist at my next visit my theory
. haha

April 6, 2014 - 1:09am
EmpowHER Guest
Anonymous (reply to Anonymous)

You wrote this 3 years ago but I had to say I'm going through a very similar realization right now. I just noticed the pattern and my mania/ovulation correlation.

Thanks for at least showing me I'm not alone.

May 25, 2017 - 10:13pm

I'm not sure I can follow the logic of the post above. But, it is true that oral contraceptives completely interrupt your own hormone regulation: your ovaries don't produce hormones anymore when you are taking them as a pill (or any other form.) While some women are estrogen dominant and respond well to progesterone, birth control does not selectively interrupt just progesterone. In order to mimic your natural menstrual cycle they contain progesterone.
The body's endocrine system and the relationship of estrogen and progesterone are intricate and complex, and any simple answer is very likely overlooking something crucial. And any simple solution - like the progesterone cream that some recommend - probably is disturbing the natural balance of estrogen, testosterone, and other hormones.
Daniel Heller, ND

December 6, 2011 - 9:56am
EmpowHER Guest
Anonymous (reply to Dr. Daniel Heller)

"And any simple solution - like.....- probably is disturbing the natural balance of estrogen, testosterone, and other hormones."
Since the body is already naturally disturbed, wouldn't the natural balance need to be disturbed in order to alleviate the imbalance?

March 2, 2014 - 4:36pm
EmpowHER Guest


Agitated depression and anxiety disorders including anxiety,panic attacks, phobias, and obsessive compulsive disorder are frequent concomitants of Temporolimbic Epilepsy that often show catamenial(i.e., menstrual cycle–related) patterns of exacerbation and favorable response to hormonal treatment with progesterone or clomiphene. ( Andrew G. Herzog,Psychoneuroendocrine Aspects of Temporolimbic Epilepsy ) (PMDD is a lie)

Don't confuse the pill with natural progesterone.
The natural and synthetic progestins are not equivalent because natural progesterone is metabolized to allopregnanolone, which has very potent GABA-a mimetic and anticonvulsant action, whereas synthetic progestins are not metabolized in this way.. ( from: Klein P and Herzog AG. Endocrine aspects of partial seizures)

If you have tried a contraceptive and it made it worse or go for longer, think about this what does the pill do? It stops you from ovulating so you make no progesterone of your own! Thats why they make it worse, you were never offered a real alternative when you said this is hormonal.
PMS progesterone makes you depressed( the pill SSRI,s will work.)
PMDD is menstrual related seizures
researchers keep mixing these women together not drawing a clear line
Natrual progestorone works on a hormone imbalance
if you do not have an imbalance, get the right anticonvulsant! epilim makes you hairy SSRI,s and the pill will not work on epilepsy
all doctors do is make money out of the untreatable dumb women who trust them I got this imformation from


you watch this post come down in a hurry they can not make money from the well

AND I AM WELL bipolar has no known organic course.

November 25, 2011 - 6:20pm
EmpowHER Guest

It seems there is very little information available about PMDD treatment options. For years, many women were simply told that they have more severe cases of PMS and would just have a battle through it. Finally, after years of knowing this was not the case, there is new medical information that can help diagnose PMDD in women. pmddBut, this was just the first step in a long process to find relief. In general, PMDD can be diagnosed if there are multiple severe symptoms of PMS at any given time. Commonly, if you exhibit three or more of the symptoms of PMS at any one time, chances are you have PMDD. www.womenshealth123.com

October 13, 2011 - 10:29am
(reply to Anonymous)

This is, unfortunately, inaccurate information. There are specific diagnostic criteria for PMDD, and it is not "three or more symptoms of PMS."
Plenty of women with three PMS symptoms have mild or moderate PMS.
You can find the diagnostic criteria for PMDD on my site, pmscomfort.com, or on womenshealth.gov.

Best of Health,

Dr. Daniel Heller
PMS Comfort

October 13, 2011 - 10:40am

Great post, Anon. Hope you get a name soon!

I am definitely a fan of using omega-3 fatty acids from Fish Oil along with any psychiatric treatment. EPA and DHA appear to simply improve brain functioning no matter the condition. I had one bipolar patient whose family could literally tell whether she'd taken her fish oil that day! Most supplements work slowly, but not in that case.

Another thing, in case anyone reads this who is new to this information: SSRIs and anti-depressants, even St. John's Wort, will not work for bipolar and have the potential to make it worse. Even psychiatrists make this mistake sometimes, since bipolar can be so hard to diagnose.

And, I'm going to have to disagree with you about breastfeeding, which is very physiologically powerful. I would not be surprised if it put someone with bipolar disease into temporary remission. The body and mind are wonderful and mysterious, even when there is a health condition going on.

Dr. Daniel Heller

August 31, 2011 - 10:07pm
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